HYPERVENTILATION, BRAIN DAMAGE AND FLICKER

Post-hyperventilation apnoea in patients with brain damage.

A study of 100 subjects has confirmed that brief voluntary hyperventilation commonly causes apnoea in patients with supramedullary lesions, but not in healthy people. Apnoea was related to drowsiness rather than to the extent of the lesion; it was unrelated to the measured reduction in end-tidal carbon dioxide tension.

Hyperventilation and the brain – helpful or hazardous ? (

Hyperventilation has been a common practice in neuroanesthesia since the 1960’s. However, a review of the literature suggests that hypocapnia was not initially deliberately introduced into practice to improve operating conditions but was perhaps an inadvertent by-product of muscle relaxation and thereby the need for intermittent positive pressure ventilation (IPPV). The first clinical report of...

O12: The Heart and the Brain: Stroke Induced Heart Damage

Cardiac diseases are common post-stroke and are associated with increased morbidity and mortality. One possible mechanism of acute cardiac injury is the neurogenic myocardial damage, where the cerebral injury is disturbing the normal sympathetic and parasympathetic neuronal outflow to the heart leading to cardiac damage including myocardial infarctions. The exact mechanism is not completely und...

Optimized hyperventilation preserves 2,3-diphosphoglycerate in severe traumatic brain injury.

INTRODUCTION The concentration of 2,3-diphosphoglycerate (2,3-DPG/Hct) increases as a physiological occurrence to pH increase and hyperventilation. This response was tested in patients with severe traumatic brain injury (TBI). METHOD The concentration of 2,3-DPG/Hct was measured daily for six days in eleven patients with severe TBI in need of optimized hyperventilation because of intracranial...

Effects of Hyperventilation Can hyperventilation cause syncope?